Metabo Flex is an all natural proprietary formula manufactured in the USA at our FDA registered and GMP certified facility using state of the art precision engineered machinery and under the strictest and most sterile standards. Each ingredient is 100% plant based soy free, dairy free, vegetarian and non GMO and put through additional third party inspections and quality control to ensure high purity and votes. The only reported side effect from Metabo Flex is having to toss your baggy clothes in the trash and spend hours in the dressing room trying out new sexy tight fitting clothes. As always, I advise you to consult your doctor if you have any medical questions.